Pieter Camper (1721-89).

Pieter Roelfsema

With this motivation, the groups of Michael Groll at the Technical University of Munich and of Marcus Groettrup at the University of Konstanz have recently solved the crystal structures of both the constitutive proteasome and the immunoproteasome of mice, each with and without the epoxyketone PR957, which is the only selective inhibitor of b5i known so far. In addition, the researchers also sol...

Dmd053942 1721..1724

Epigenetic regulation of gene expression refers to heritable factors that are functionally relevant genomic modifications but that do not involve changes in DNA sequence. Examples of such modifications include DNA methylation, histone modifications, noncoding RNAs, and chromatin architecture. Epigenetic modifications are crucial for packaging and interpreting the genome, and they have fundament...

In memoriam Pieter D. Nieuwkoop (1917-1996).

Pieter Nieuwkoop died September 18, 1996, at age 79, in sues formed by the flap which protruded from the neural tube. The most anterior neural structures (forebrain) develUtrecht, The Netherlands, after a brief illness. He continued his laboratory research on early vertebrate development oped at the distal end of the flap, whereas posterior structures developed at the base and matched those of ...

Petrus Camper on the origin and color of blacks.

Pieter Bruegel’s Symbolic Highlands in the Lowlands

10 Pieter Bruegel the Elder, while best known for his representations of the landscapes and rustic inhabitants of his native Lowlands, did not restrict himself to these topics—in fact, most of his paintings address religious subjects, even when placing them in carefully constructed landscapes. When Bruegel represented biblical events, such as the Tower of Babel or the Conversion of Saint Paul, ...